The exchange between Godoy Cruz, Argentina, and Peñalolén, Chile, contributed to the strengthening of the partnership between the two cities and between them and Peace in Our Cities (PioC). It offered both cities valuable insights into local strategies for violence prevention, highlighting the critical role of strong local leadership to drive cities to invest in violence prevention and the fact that quality data is crucial for informed and efficient decision-making and community engagement. Both cities emphasized the importance of institutionalizing observatories, integrating diverse data sources into them, and continuously adapting their data systems to local needs. The experiences emphasized the need for tailored, context-sensitive interventions, investment in local technical capacity, and a balanced approach that combines evidence-based social prevention programs with other public safety tools, including preventative community policing. These lessons will inform both cities’ commitments to effective and inclusive urban security policies.